Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions. [ DOI:10.1002/glia.20642 Wikipedia:Blood-brain_barrier ]
术语信息
- null:http://uri.neuinfo.org/nif/nifstd/nlx_subcell_100205
- UMLS:C0005854 (ncithesaurus:Blood-Brain_Barrier)
- NCIT:C13194
- Wikipedia:Blood-brain_barrier
Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions.
术语关系
- anatomical entity
- cell layer
- part of some nervous system
- adjacent to some haemolymphatic fluid
- adjacent to some brain