A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. [ Wikipedia:Germinal_center CL:tm https://orcid.org/0000-0002-6601-2165 ]
术语信息
- Wikipedia:Germinal_center
- UMLS:C0282491 (ncithesaurus:Germinal_Center)
- EV:0100051
- SCTID:64626006
- BTO:0003671
- NCIT:C13337
- MESH:D018858
A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO]
A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center.