An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. [ GO_REF:0000031 GOC:tfm GOC:dsd PMCID:PMC2673126 GOC:msz ]
术语信息
- FMA:84371
This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative.
An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative.
术语关系
- mature B cell and produces some immunoglobulin complex, circulating and has_high_plasma_membrane_amount some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has_high_plasma_membrane_amount some CD27 molecule and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some syndecan-1
- antibody secreting cell
- mature B cell
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- has part some CD27 molecule
- has_high_plasma_membrane_amount some CD27 molecule
- has_high_plasma_membrane_amount some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- has part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- develops from some mature B cell
- lacks_plasma_membrane_part some syndecan-1