A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. [ GOC:add GOC:dsd ISBN:0781735149 ]
术语信息
Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.
A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen.
术语关系
- B cell, CD19-positive and capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and capable of some B cell activation and has_completed some mature B cell differentiation
- professional antigen presenting cell
- B cell, CD19-positive
- develops from some transitional stage B cell
- capable of some B cell activation
- has_completed some mature B cell differentiation