A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. [ PMID:19855402 GOC:tfm PMID:22043829 PMID:20107805 ]
术语信息
A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production.
follicular helper T-cell
follicular T cell
follicular B helper T cell
follicular T-helper cell
follicular T-cell
follicular helper T cell
术语关系
- CD4-positive helper T cell and has part some B-cell lymphoma 6 protein and has plasma membrane part some C-X-C chemokine receptor type 5 and has plasma membrane part some inducible T-cell costimulator and has plasma membrane part some programmed cell death protein 1 and capable of some positive regulation of isotype switching and capable of some GO_0051024 and lacks_plasma_membrane_part some C-C chemokine receptor type 7
- CD4-positive helper T cell
- capable of some GO_0051024
- has part some C-X-C chemokine receptor type 5
- has plasma membrane part some programmed cell death protein 1
- lacks_plasma_membrane_part some C-C chemokine receptor type 7
- capable of some positive regulation of isotype switching
- has plasma membrane part some inducible T-cell costimulator
- has part some inducible T-cell costimulator
- has part some programmed cell death protein 1
- has plasma membrane part some C-X-C chemokine receptor type 5
- has part some B-cell lymphoma 6 protein