A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. [ PMID:15514007 GOC:add PMID:12560239 ISBN:0721601464 ]
术语信息
These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-negative, CD49d-positive, CD68-positive, lactotransferrin-negative, and fMLP receptor-negative. They are found in the Band 3 fraction.
A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor.
术语关系
- myeloblast and has part some transcription factor PU.1 and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and has part some myb proto-oncogene protein and has part some runt-related transcription factor 1 and capable of some neutrophil differentiation
- myeloblast
- neutrophil progenitor cell
- has part some myb proto-oncogene protein
- has part some runt-related transcription factor 1
- has part some transcription factor PU.1
- has part some CCAAT/enhancer-binding protein alpha
- has part some erythroid transcription factor
- develops from some neutrophil progenitor cell