A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. [ GOC:tfm ISBN:0781735149 GO_REF:0000031 GOC:add ]
术语信息
Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and beginning to rearrange the T cell receptor alpha chain.
A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive.
DN4 immature T cell
double negative 4
DN4 immature T-cell
DN4 alpha-beta immature T lymphocyte
DN4 alpha-beta immature T-lymphocyte
DN4 cell
T.DN4.th
术语关系
- thymocyte and has plasma membrane part some pre-T cell receptor complex and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some CD44 molecule and lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha and lacks_plasma_membrane_part some T cell receptor co-receptor CD8