naive thymus-derived CD4-positive, alpha-beta T cell
Go to external page http://purl.obolibrary.org/obo/CL_0000895
An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. [ GO_REF:0000031 GOC:add GOC:tfm PMID:22343568 http://www.immgen.org/index_content.html PMID:19100699 ]
术语信息
These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells.
An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low.
naive thymus-derived CD4-positive, alpha-beta T lymphocyte
naive thymus-derived CD4-positive, alpha-beta T-cell
naive thymus-derived CD4-positive, alpha-beta T-lymphocyte
T.4Nve.Sp
Th0
术语关系
- CD4-positive, alpha-beta T cell and has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45RA and has plasma membrane part some C-C chemokine receptor type 7 and has plasma membrane part some interleukin-7 receptor subunit alpha and has_high_plasma_membrane_amount some L-selectin and has_low_plasma_membrane_amount some CD44 molecule and lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha