A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low. [ GO_REF:0000031 GOC:ana PMID:19644016 ]
术语信息
Markers: Mouse: F4/80+, CD68+, MR+, Dectin2+, macrosialin+, sialoadhesin-low; role or process: immune, clearance of senescent erythrocytes.
A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low.
术语关系
- splenic macrophage and part of some red pulp of spleen and has plasma membrane part some C-type lectin domain family 6 member A and has plasma membrane part some adhesion G protein-coupled receptor E1 and has plasma membrane part some macrosialin and has plasma membrane part some macrophage mannose receptor 1 and capable of some immune response and capable of some erythrocyte clearance and has_low_plasma_membrane_amount some integrin alpha-M and has_low_plasma_membrane_amount some sialoadhesin and lacks_plasma_membrane_part some integrin alpha-X
- splenic macrophage
- has plasma membrane part some macrophage mannose receptor 1
- has part some adhesion G protein-coupled receptor E1
- lacks_plasma_membrane_part some integrin alpha-X
- part of some red pulp of spleen
- has part some integrin alpha-M
- has part some sialoadhesin
- capable of some immune response
- has_low_plasma_membrane_amount some sialoadhesin
- has part some macrophage mannose receptor 1
- has plasma membrane part some adhesion G protein-coupled receptor E1
- has part some C-type lectin domain family 6 member A
- has_low_plasma_membrane_amount some integrin alpha-M
- has part some macrosialin
- has plasma membrane part some macrosialin
- has plasma membrane part some C-type lectin domain family 6 member A