A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. [ PMID:19231594 GOC:tfm http://www.cap.org ISBN:0721601464 GOC:add PMID:20837449 GOC:dsd PMID:18466030 ]
术语信息
- CALOHA:TS-0688
- BTO:0001026
Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4.
A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation.
术语关系
- basophil and has part some (
nucleus and
bearer of some lobed) and capable of some histamine production involved in inflammatory response and capable of some serotonin production involved in inflammatory response and capable of some positive regulation of type 2 immune response and capable of some blood circulation and capable of some interleukin-13 production and capable of some interleukin-4 production and capable of some positive regulation of isotype switching to IgE isotypes
- histamine secreting cell
- basophil
- capable of some interleukin-4 production
- has part some (
nucleus and
bearer of some lobed) - capable of some histamine production involved in inflammatory response
- capable of some positive regulation of type 2 immune response
- capable of some interleukin-13 production
- capable of some positive regulation of isotype switching to IgE isotypes
- capable of some serotonin production involved in inflammatory response
- develops from some band form basophil