A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. [ PMID:16213494 GO_REF:0000031 GOC:tfm GOC:add PMID:1919437 ]
术语信息
- FMA:63261
- FMA:83585
- CALOHA:TS-0587
- BTO:0000801
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
术语关系
- myeloid leukocyte and capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and capable of some phagocytosis and capable of some pseudopodium organization