A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. [ PMID:20081059 GOC:add PMID:20839338 GOC:dsd ISBN:0781735149 GO_REF:0000031 http://en.wikipedia.org/wiki/Memory_B_cell GOC:rhs ]
术语信息
Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive.
A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative.
术语关系
- mature B cell and has plasma membrane part some MHC class II protein complex and has plasma membrane part some membrane-spanning 4-domains subfamily A member 1 and has_completed some B cell affinity maturation and lacks_plasma_membrane_part some syndecan-1
- mature B cell
- has part some MHC class II protein complex
- has part some membrane-spanning 4-domains subfamily A member 1
- has_completed some B cell affinity maturation
- has plasma membrane part some membrane-spanning 4-domains subfamily A member 1
- has plasma membrane part some MHC class II protein complex
- lacks_plasma_membrane_part some syndecan-1