A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. [ GOC:add GO_REF:0000031 ISBN:0781735149 GOC:tfm ]
术语信息
A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain.
TN3 thymocyte
preT.DN3.Th
DN3 cell
double negative 3
TN3 cell
DN3 alpha-beta immature T-lymphocyte
DN3 immature T cell
DN3 alpha-beta immature T-cell
DN3 alpha-beta immature T lymphocyte
术语关系
- thymocyte and has plasma membrane part some pre-T cell receptor complex and has plasma membrane part some interleukin-2 receptor subunit alpha and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some CD44 molecule and lacks_plasma_membrane_part some T cell receptor co-receptor CD8
- thymocyte
- double negative thymocyte
- develops from some DN2 thymocyte
- has part some interleukin-2 receptor subunit alpha
- has part some pre-T cell receptor complex
- has plasma membrane part some interleukin-2 receptor subunit alpha
- lacks_plasma_membrane_part some CD44 molecule
- has plasma membrane part some pre-T cell receptor complex