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ATPase-coupled transmembrane transporter activity

Go to external page http://purl.obolibrary.org/obo/GO_0042626

Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. [ GOC:mtg_transport ISBN:0815340729 ]

This is just here as a test because I lose it

术语信息

database cross reference
  • Reactome:R-HSA-1467457 (ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region)
  • Reactome:R-HSA-9033499 (PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol)
  • Reactome:R-HSA-9033505 (PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12)
  • Reactome:R-HSA-2161506 (abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate)
  • Reactome:R-HSA-2161538 (abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate)
definition

Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.

has alternative id

GO:0043492

GO:0015405

GO:0016820

has broad synonym

P-P-bond-hydrolysis-driven transporter

ATPase activity, coupled to movement of substances

P-P-bond-hydrolysis-driven transmembrane transporter activity

has exact synonym

ATP-coupled transmembrane transporter activity

ATP-dependent transmembrane transporter activity

ATPase activity, coupled to transmembrane movement of substances

has narrow synonym

hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

has obo namespace

molecular_function

id

GO:0042626

term tracker item

https://github.com/geneontology/go-ontology/issues/17373

https://github.com/geneontology/go-ontology/issues/14642

https://github.com/geneontology/go-ontology/issues/19965