The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. [ GOC:go_curators ]
术语信息
- Wikipedia:Translation_(genetics)
goslim_chembl, goslim_generic, goslim_metagenomics, goslim_pir, goslim_plant, goslim_candida, goslim_aspergillus
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
protein formation
protein translation
protein biosynthesis
protein anabolism
protein biosynthetic process
protein synthesis
术语关系
- peptide biosynthetic process
- cellular macromolecule biosynthetic process
- cellular protein metabolic process
- part of some gene expression
- has part some translational elongation
- translation factor activity, RNA binding
- regulation of translation by machinery localization
- N-terminal peptidyl-proline dimethylation involved in translation
- triplet codon-amino acid adaptor activity
- tRNA aminoacylation for protein translation
- translational termination
- translational elongation
- translational initiation
- peptidyltransferase activity
- maintenance of translational fidelity