Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. [ RHEA:13065 ]
术语信息
- Reactome:R-HSA-6814683 (NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN)
- Reactome:R-HSA-8939203 (HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex)
- Reactome:R-HSA-6811422 (NSF ATPase activity dissociates cis-SNARE at the ER)
- Reactome:R-HSA-9609860 (Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP)
- Reactome:R-HSA-917693 (ESCRT Disassembly)
- Reactome:R-HSA-5694425 (NSF ATPase activity dissociates cis-SNARE)
- RHEA:13065
- Reactome:R-HSA-9668415 (VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope)
- Reactome:R-HSA-9038161 (Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG)
- Reactome:R-HSA-9706399 (RHOBTB3 hydrolyzes ATP)
- Reactome:R-HSA-6814670 (ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation)
- Reactome:R-HSA-416985 (Trafficking of GluR2-containing AMPA receptors to synapse)
- Reactome:R-HSA-5654989 (SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA)
- Reactome:R-HSA-3371422 (ATP hydrolysis by HSP70)
- Reactome:R-HSA-5618093 (ATP hydrolysis by HSP90)
- Reactome:R-HSA-72139 (Formation of the active Spliceosomal C (B*) complex)
- Reactome:R-HSA-6814678 (ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN)
- Reactome:R-HSA-159101 (NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B))
- Reactome:R-HSA-6809015 (NSF ATPase activity dissociates cis-SNARE at cis-Golgi)
- Reactome:R-HSA-8847638 (ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane)
- Reactome:R-HSA-8868658 (HSPA8-mediated ATP hydrolysis promotes vesicle uncoating)
Note that this term is meant to specifically represent the ATPase activity of proteins using ATPase as a source of energy to drive a reaction. If possible, gene products should also be annotated to a child of 'ATP-dependent activity ; GO:0140657', to capture their overall function.
Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP phosphohydrolase activity
adenosinetriphosphatase activity
ATP hydrolase activity
adenosine 5'-triphosphatase activity
adenosine triphosphatase activity
https://github.com/geneontology/go-ontology/issues/19078
https://github.com/geneontology/go-ontology/issues/21612
https://github.com/geneontology/go-ontology/issues/20498