Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins. [ GOC:txnOH-2018 ]
术语信息
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
DNA-dependent RNA polymerase promoter selection factor
sigma factor activity
sigma transcription factor
core DNA-dependent RNA polymerase binding promoter specificity activity
promoter selection factor activity
bacterial sigma factor activity
plastid sigma factor activity
https://github.com/geneontology/go-ontology/issues/15587
https://github.com/geneontology/go-ontology/issues/14848