The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded. [ PMID:22743996 PMID:23434281 GOC:PARL GOC:pad ]
术语信息
- Wikipedia:Chaperone-mediated_autophagy
The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.
术语关系
- autophagy
- protein catabolic process
- has part some signaling receptor binding
- has part some protein carrier activity