Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. [ ISBN:0198547684 GOC:mah ]

This is just here as a test because I lose it

术语信息

database cross reference
  • Reactome:R-HSA-5686440 (MUS81:EME1,EME2 cleaves D-loop)
  • Reactome:R-HSA-9023941 (MRN:CtIP endonucleolytically cleaves single-strand DNA 3' to SPO11)
  • Reactome:R-HSA-6782204 (5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER)
  • Reactome:R-HSA-5690988 (3'-incision of DNA by ERCC5 (XPG) in GG-NER)
  • Reactome:R-HSA-5687464 (MRN and RBBP8 resect DNA DSBs in MMEJ)
  • Reactome:R-HSA-5693608 (Initial resection of double-strand break ends)
  • Reactome:R-HSA-6782224 (3' incision by ERCC5 (XPG) in TC-NER)
  • Reactome:R-HSA-5686657 (ERCC1:XPF cleaves flaps generated by SSA)
  • Reactome:R-HSA-5693584 (Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2))
  • Reactome:R-HSA-110359 (APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site)
definition

Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.

has obo namespace

molecular_function

has related synonym

DNA nicking activity

endonuclease G activity

id

GO:0004520