JSON

protein tyrosine phosphatase activity

Go to external page http://purl.obolibrary.org/obo/GO_0004725

Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. [ EC:3.1.3.48 ]

This is just here as a test because I lose it

术语信息

database cross reference
  • Reactome:R-HSA-8867047 (PTPN3 dephosphorylates EPS15)
  • Reactome:R-HSA-391868 (Dephosphorylation of NCAM1 bound pFyn)
  • Reactome:R-HSA-8864125 (PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248)
  • Reactome:R-HSA-1169210 (PTP1B dephosphorylates JAK2)
  • Reactome:R-HSA-997311 (Dephosphorylation of TYK2 by PTP1B)
  • Reactome:R-HSA-8864029 (PTPN12 dephosphorylates EGFR at Y1148 (Y1172))
  • RHEA:10684
  • Reactome:R-HSA-74733 (Insulin receptor de-phosphorylation)
  • Reactome:R-HSA-8937767 (PTPN11 dephosphorylates RUNX1)
  • Reactome:R-HSA-389758 (Dephosphorylation of CD3-zeta by PD-1 bound phosphatases)
  • MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN
  • Reactome:R-HSA-8855381 (PTPN22 dephosphorylates ZAP70)
  • Reactome:R-HSA-6807008 (PTPRJ dephosphorylates MET)
  • Reactome:R-HSA-8867658 (PTPN3 dephosphorylates MAPK12)
  • Reactome:R-HSA-445089 (Dephosphorylation of pL1 (Y1176))
  • Reactome:R-HSA-8852200 (Inactivation of LCK by PTPN22)
  • Reactome:R-HSA-74747 (Dephosphorylation of p-Y-IRS1,p-Y-IRS2)
  • Reactome:R-HSA-377643 (Dephosphorylation of inactive SRC by PTPB1)
  • Reactome:R-HSA-997326 (Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP)
  • Reactome:R-HSA-5683967 (EYA1-4 dephosphorylates tyrosine Y142 of H2AFX)
  • Reactome:R-HSA-914036 (SHP1 and SHP2 dephosphorylate Y628 of IL3RB)
  • Reactome:R-HSA-6807027 (PTPN1 and PTPN2 dephosphorylate MET)
  • Reactome:R-HSA-1549564 (PPTN11 dephosphorylates SPRY2)
  • Reactome:R-HSA-1169188 (SHP1 (PTPN6) dephosphorylates JAK2)
  • Reactome:R-HSA-74748 (De-phosphorylation of p-Y427-SHC1)
  • Reactome:R-HSA-8864036 (PTPN12 dephosphorylates PDGFRB at Y1021)
  • Reactome:R-HSA-8849435 (PTPN1 dephosphorylates PTK6)
  • EC:3.1.3.48
  • Reactome:R-HSA-877308 (Dephosphorylation of JAKs by PTPs)
  • Reactome:R-HSA-9636439 (PtpA:Ub dephosphorylates p-Y133-VPS33B)
  • Reactome:R-HSA-997314 (Dephosphorylation of JAK1 by SHP1)
  • Reactome:R-HSA-8863804 (PTPN12 dephosphorylates ERBB2 on tyrosine Y1248)
  • Reactome:R-HSA-997309 (Dephosphorylation of STAT1 by SHP2)
  • Reactome:R-HSA-1169192 (PTP1B dephosphorylates GHR)
  • Reactome:R-HSA-9698408 (PTPRJ dephosphorylates active FLT3)
  • Reactome:R-HSA-203797 (ERKs are inactivated by dual-specific phosphatases (DUSPs))
  • Reactome:R-HSA-9635461 (PtpA dephosphorylates GSK3A)
  • Reactome:R-HSA-202214 (Dephosphorylation of Lck-pY505 by CD45)
  • Reactome:R-HSA-9603719 (Protein tyrosine phosphatases dephosphorylate NTRK3)
definition

Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

has obo namespace

molecular_function

has related synonym

PTPase activity

phosphotyrosine histone phosphatase activity

protein phosphotyrosine phosphatase activity

[phosphotyrosine]protein phosphatase activity

PTP-phosphatase activity

tyrosylprotein phosphatase activity

phosphotyrosine phosphatase activity

phosphotyrosylprotein phosphatase activity

phosphotyrosine protein phosphatase activity

PPT-phosphatase activity

protein-tyrosine-phosphate phosphohydrolase activity

tyrosine O-phosphate phosphatase activity

protein-tyrosine-phosphatase activity

phosphoprotein phosphatase (phosphotyrosine) activity

id

GO:0004725