Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. [ PMID:26517899 ]
术语信息
- Reactome:R-HSA-5223313 (ABCD4 may transport Cbl from lysosomal lumen to cytosol)
- Wikipedia:ATP-binding_cassette_transporter
- Reactome:R-HSA-9661405 (ABCC1 transports BIL from cytosol to extracellular region (blood))
- Reactome:R-HSA-5362459 (VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol)
- Reactome:R-HSA-5387389 (Hh processing variants are translocated to the cytosol in a VCP-dependent manner)
- Reactome:R-HSA-5683325 (Defective ABCD4 does not transport Cbl from lysosomal lumen to cytosol)
- TC:3.A.1
- Reactome:R-HSA-266070 (LTC4 is exported from the cytosol by ABCC1)
Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
ABC-type uptake permease activity
ABC-type efflux permease activity
ATP binding cassette transporter
ABC-type efflux porter activity
ABC-type transmembrane transporter activity
ATP-binding cassette transporter
ABC transporter
ATP-binding cassette (ABC) transporter activity
https://github.com/geneontology/go-ontology/issues/21273
https://github.com/geneontology/go-ontology/issues/20529