An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. [ GOC:add GOC:dsd PMID:20933013 ISBN:0781765196 GO_REF:0000031 GOC:rhs PMID:22343568 ]
术语信息
This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.
An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative.
unswitched memory B lymphocyte
unswitched memory B-cell
unswitched memory B-lymphocyte
non-class-switched memory B cell
术语关系
- memory B cell and has plasma membrane part some IgD immunoglobulin complex and has plasma membrane part some IgM immunoglobulin complex and has plasma membrane part some CD27 molecule and lacks_plasma_membrane_part some IgG immunoglobulin complex and lacks_plasma_membrane_part some IgE immunoglobulin complex and lacks_plasma_membrane_part some IgA immunoglobulin complex and lacks_plasma_membrane_part some syndecan-1
- memory B cell
- lacks_plasma_membrane_part some IgG immunoglobulin complex
- lacks_plasma_membrane_part some IgA immunoglobulin complex
- develops from some plasmablast
- has plasma membrane part some IgD immunoglobulin complex
- has part some CD27 molecule
- has part some IgD immunoglobulin complex
- has plasma membrane part some CD27 molecule
- lacks_plasma_membrane_part some IgE immunoglobulin complex
- has part some IgM immunoglobulin complex
- has plasma membrane part some IgM immunoglobulin complex