A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. [ GOC:amm http://www.cap.org ISBN:0721601464 GOC:add GOC:tfm ]
术语信息
- FMA:83530
- CALOHA:TS-0825
A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative.
术语关系
- myeloid lineage restricted progenitor cell and has part some basophilic cytoplasm and has part some increased nucleus size and has part some nucleolus and has part some azurophil granule and has plasma membrane part some alpha-(1,3)-fucosyltransferase 4 and has plasma membrane part some CD33 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some low affinity immunoglobulin gamma Fc region receptor III and lacks_plasma_membrane_part some signal transducer CD24
- granulocytopoietic cell
- myeloid cell
- myeloid lineage restricted progenitor cell
- has part some increased nucleus size
- has part some nucleolus
- has plasma membrane part some alpha-(1,3)-fucosyltransferase 4
- develops from some myeloblast
- lacks_plasma_membrane_part some signal transducer CD24
- lacks_plasma_membrane_part some low affinity immunoglobulin gamma Fc region receptor III
- has part some azurophil granule
- has part some CD33 molecule
- has part some basophilic cytoplasm
- lacks_plasma_membrane_part some integrin alpha-M
- has part some alpha-(1,3)-fucosyltransferase 4
- has plasma membrane part some CD33 molecule