A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. [ MESH:D017628 PMID:14612429 PMID:12430718 PMID:16177057 GOC:add PMID:14561199 GOC:dsd PMID:19461673 http://en.wikipedia.org/wiki/Microglia GOC:tfm PMID:11517395 PMID:2089275 ISBN:0721601464 ]
术语信息
- BTO:0000962
- BTO:0000078
- FMA:54539
- FMA:54540
Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive.
A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.
术语关系
- glial cell and part of some central nervous system and has plasma membrane part some integrin alpha-M and has plasma membrane part some adhesion G protein-coupled receptor E1 and has plasma membrane part some macrosialin and capable of some innate immune response
- central nervous system macrophage
- glial cell
- has part some adhesion G protein-coupled receptor E1
- has part some integrin alpha-M
- has plasma membrane part some integrin alpha-M
- has part some macrosialin
- has plasma membrane part some macrosialin
- has plasma membrane part some adhesion G protein-coupled receptor E1
- develops from some oligodendrocyte precursor cell
- capable of some innate immune response