A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. [ GOC:add ISBN:0702022918 ISBN:0702024783 GOC:tfm ]
术语信息
- BTO:0003107
- FMA:83035
Role or process: Chronic infection, granulomatous inflammation. Consider also megakaryocyte (CL:0000556) as sometimes multinucleated giant cell is used to refer to this.
A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes.
syncytial giant cell
multinucleate giant cell
macrophage polykaryon
foreign body giant cell
Langerhans giant cell
术语关系
- myeloid leukocyte and bearer of some multinucleate and participates in some granuloma formation and participates in some chronic inflammatory response