A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. [ http://www.cap.org MESH:A11.118.637.415.583 PMID:11138776 PMID:15514007 PMID:7880385 GOC:add PMID:12560239 GOC:tfm MESH:D009504 ]
术语信息
- BTO:0003473
Neutrophils are also capable of secreting GRO-alpha, IL-1beta, IL-1ra, IL-3, IL-12, IP-10, MIG, MIP-1alpha, MIP-1beta, TGF-beta, TNF-alpha, VEGF, and anti-microbial peptides. They can positively influence the chemotaxis of basophils, T-cells, monocytes, macrophages, dendritic cells, and other neutrophils. Neutrophils are also CD35-positive, CD64-positive, CD89-positive, CD184-positive, and fMLP receptor-positive Ly-6G-positive (mouse), TLR2-low, TLR4-low, and lineage-negative (CD2, CD3, CD5, CD9, CD19, CD36, CD49d, CD56, CD61, CD235a (glycophorin-A)).
A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive.
PMN
polynuclear neutrophilic leukocyte
mature neutrophilic leucocyte
mature neutrophilic leukocyte
mature neutrocyte
mature neutrophil leucocyte
mature neutrophil leukocyte
polymorphonuclear neutrophil
polynuclear neutrophilic leucocyte
术语关系
- neutrophil and has part some neutrophillic cytoplasm and has part some tertiary granule and has part some (
nucleus and
bearer of some lobed) and has plasma membrane part some C-X-C chemokine receptor type 1 and has plasma membrane part some C-X-C chemokine receptor type 2 and has plasma membrane part some alpha-(1,3)-fucosyltransferase 4 and has plasma membrane part some low affinity immunoglobulin gamma Fc region receptor III and has plasma membrane part some leukosialin and has plasma membrane part some transcription factor PU.1 and has plasma membrane part some proto-oncogene c-Fos and capable of some respiratory burst involved in inflammatory response and capable of some positive regulation of leukocyte chemotaxis and capable of some phagocytosis and capable of some interleukin-8 production and lacks_part some lactotransferrin and lacks_part some myeloperoxidase and lacks_part some myb proto-oncogene protein
- phagocyte
- neutrophil
- has plasma membrane part some transcription factor PU.1
- capable of some positive regulation of leukocyte chemotaxis
- has part some transcription factor PU.1
- has part some C-X-C chemokine receptor type 2
- lacks_part some lactotransferrin
- has plasma membrane part some C-X-C chemokine receptor type 1
- has part some (
nucleus and
bearer of some lobed) - lacks_part some myb proto-oncogene protein
- has part some neutrophillic cytoplasm
- has plasma membrane part some alpha-(1,3)-fucosyltransferase 4
- has part some low affinity immunoglobulin gamma Fc region receptor III
- has part some proto-oncogene c-Fos
- has part some tertiary granule
- has plasma membrane part some proto-oncogene c-Fos
- capable of some respiratory burst involved in inflammatory response
- has plasma membrane part some C-X-C chemokine receptor type 2
- lacks_part some myeloperoxidase
- has part some alpha-(1,3)-fucosyltransferase 4
- capable of some interleukin-8 production
- has part some C-X-C chemokine receptor type 1
- has plasma membrane part some low affinity immunoglobulin gamma Fc region receptor III