Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. [ GOC:mah ISBN:0198547684 ]
术语信息
database
cross reference
- Reactome:R-HSA-72180 (Cleavage of mRNA at the 3'-end)
- Reactome:R-HSA-5358518 (MLH1:PMS2 makes single strand incision near 1-2 base mismatch)
- Reactome:R-HSA-5358512 (MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more)
- Reactome:R-HSA-5690990 (5'- incision of DNA by ERCC1:ERCC4 in GG-NER)
- Reactome:R-HSA-5693533 (DCLRE1C (ARTEMIS) processes DNA DSB ends)
definition
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.