Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. [ GOC:txnOH ]
术语信息
- Reactome:R-HSA-6814549 (Pre-snRNA transcript initiation, Integrator binding, LEC binding)
- Reactome:R-HSA-6814559 (Pre-snRNA is elongated and capped with 7-methylguanosine)
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter